| 名稱 | NRAS p.G12C Reference Standard 標(biāo)準(zhǔn)品 |
| 型號 | CBP10315 |
| 報價 |  |
| 特點 | NRAS p.G12C Reference Standard |
產(chǎn)品搜索
相關(guān)文章
聯(lián)系我們
聯(lián)系人：蔣經(jīng)理
電話：4008750250
號碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號
Email： zhangxiangwen@cobioer.com
電話：4008750250
號碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號
Email： zhangxiangwen@cobioer.com
產(chǎn)品展示 / PRODUCTS
基因檢測標(biāo)準(zhǔn)品 > Mutation > CBP10315NRAS p.G12C Reference Standard 標(biāo)準(zhǔn)品
- 詳細(xì)內(nèi)容
" _ue_custom_node_="true">
CBP10315 | |
| Format | Genomic DNA |
| Description | NRAS G12C is a hotspot mutation that lies within a GTP-binding region of the Nras protein (UniProt.org). G12C has not been characterized, but can be predicted to confer a loss of function on Nras protein based on the effects of HRAS G12C and KRAS G12C, which result in a loss of response to GTPase-activating proteins, and transformation of cultured cells (PMID: 26037647, PMID: 6092966). |
| Technical Data | |
| DNA Change | c.34G>T |
| AA Change | p.G12C |
| Mutation type | Substitution - Missense |
| Zygosity | Heterozygous |
| Allelic Frequency | 25.00% |
| Transcript | ENST00000369535 |
| Cosmic ID | COSM562 |
| Chr position(GRCh37) | chr1:115258748 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
|
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
